5VC8
Crystal structure of the WHSC1 PWWP1 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Histone-lysine N-methyltransferase NSD2 | polymer | 141 | 16207.2 | 2 | UniProt (O96028) Pfam (PF00855) In PDB | Homo sapiens (Human) | Multiple myeloma SET domain-containing protein,MMSET,Nuclear SET domain-containing protein 2,Protein trithorax-5,Wolf-Hirschhorn syndrome candidate 1 protein |
| 2 | W, X, Y | dodeca-2-deoxy-nucleotide, poorly resolved by electron density | polymer | 12 | 3662.4 | 3 | synthetic construct | ||
| 3 | Z | DNA (5'-D(P*CP*TP*(DN))-3') | polymer | 3 | 728.5 | 1 | synthetic construct | ||
| 4 | B, A | UNKNOWN ATOM OR ION | non-polymer | 39 | Chemie (UNX) | ||||
| 5 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A, B: 211 - 350 (UniProt: O96028)
| PDB | External Database | Details |
|---|---|---|
| Gly 210 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 44130.1 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 0.0 | |
| All* | Total formula weight | 44130.1 |
