5VBE
Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | GTPase HRas | polymer | 171 | 19250.6 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (Human) | H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras |
2 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
3 | A | 1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide | non-polymer | 359.4 | 1 | Chemie (92V) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01112)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Cys 72 | Met 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19250.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 826.9 | |
All* | Total formula weight | 20077.5 |