5VAR
Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Lysine-specific demethylase 4A | polymer | 119 | 13542.9 | 1 | UniProt (O75164) Pfam (PF18104) In PDB | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A |
| 2 | A | (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol | non-polymer | 245.4 | 1 | Chemie (92Y) | |||
| 3 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 897 - 1011 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Gly 893 | - | expression tag |
| Ser 894 | - | expression tag |
| His 895 | - | expression tag |
| Met 896 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13542.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 245.4 | |
| All* | Total formula weight | 13788.3 |
