5VAN
Crystal Structure of Beta-Klotho
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-klotho | polymer | 954 | 109594.4 | 1 | UniProt (Q86Z14) Pfam (PF00232) | Homo sapiens (Human) | BetaKlotho,Klotho beta-like protein |
| 2 | B (B) | Nb914 | polymer | 134 | 14837.5 | 1 | Lama glama | ||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E, F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | G, H (A) | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
| 6 | I, J (A) | beta-D-glucopyranose | non-polymer | 180.2 | 2 | Chemie (BGC) | |||
| 7 | K (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 8 | L, M (A, B) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
A: 30 - 983 (UniProt: Q86Z14)
| PDB | External Database | Details |
|---|---|---|
| Gln 308 | Asn 308 | engineered mutation |
| Gln 611 | Asn 611 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 124431.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1579.5 | |
| All* | Total formula weight | 126435.7 |
