5VA8

Crystal Structure of Short-chain dehydrogenase/reductase SDR from Burkholderia phymatum in complex with NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Short-chain dehydrogenase/reductase SDR	polymer	267	27776.6	4	UniProt (B2JE32) Pfam (PF13561)	Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)
2	E, H, J, M (A, B, C, D)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
3	F, I, K, N (A, B, C, D)	3,3',3''-phosphanetriyltripropanoic acid	non-polymer		250.2	4	Chemie (TCE)
4	G, L, O (A, C, D)	3[N-MORPHOLINO]PROPANE SULFONIC ACID	non-polymer		209.3	3	Chemie (MPO)
5	P, Q, R, S (A, B, C, D)	water	water		18.0	1293	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 259 (UniProt: B2JE32)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	111106.2
Non-Polymers*	Number of molecules	11
	Total formula weight	4602.2
All*	Total formula weight	115708.4

*Water molecules are not included.