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5V8W

Crystal structure of human Integrator IntS9-IntS11 CTD complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
Integrator complex subunit 9polymer789003.44UniProt (Q9NV88)
Pfam (PF21382)
Homo sapiens (Human)Int9,Protein related to CPSF subunits of 74 kDa,RC-74
2B, D, F, H
(B, D, F, H)
Integrator complex subunit 11polymer11412673.44UniProt (Q5TA45)
Pfam (PF21386)
Homo sapiens (Human)Int11,Cleavage and polyadenylation-specific factor 3-like protein,CPSF3-like protein,Protein related to CPSF subunits of 68 kDa,RC-68
3I, J, K, L, M...
(A, B, C, D, E...)
waterwater18.0419Chemie (HOH)
Sequence modifications
A, C, E, G: 582 - 658 (UniProt: Q9NV88)
PDBExternal DatabaseDetails
Met 581-initiating methionine
B, D, F, H: 491 - 600 (UniProt: Q5TA45)
PDBExternal DatabaseDetails
Gly 487-expression tag
Ser 488-expression tag
His 489-expression tag
Met 490-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight86707.3
All*Total formula weight86707.3
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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