5V6E

Crystal structure of Myosin VI in complex with GH2 domain of GIPC1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I (A, C, E, G, I)	PDZ domain-containing protein GIPC1	polymer	80	8963.0	5	UniProt (Q9Z0G0)	Mus musculus (Mouse)	GAIP C-terminus-interacting protein,RGS-GAIP-interacting protein,RGS19-interacting protein 1,SemaF cytoplasmic domain-associated protein 1,SEMCAP-1,Synectin
2	B, D, F, H, J (B, D, F, H, J)	Unconventional myosin-VI	polymer	49	5786.6	5	UniProt (Q64331)	Mus musculus (Mouse)	Unconventional myosin-6

Sequence modifications

A, C, E, G, I: 258 - 333 (UniProt: Q9Z0G0)

PDB	External Database	Details
Gly 254	-	expression tag
Pro 255	-	expression tag
His 256	-	expression tag
Met 257	-	expression tag

B, D, F, H, J: 1052 - 1096 (UniProt: Q64331)

PDB	External Database	Details
Gly 1048	-	expression tag
Pro 1049	-	expression tag
Gly 1050	-	expression tag
Ser 1051	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	73747.7
All*	Total formula weight	73747.7

*Water molecules are not included.