5V58
Crystal structure of human prolyl-tRNA synthetase in complex with Aze-SA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional glutamate/proline--tRNA ligase | polymer | 519 | 59063.5 | 1 | UniProt (P07814) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Homo sapiens (Human) | Bifunctional aminoacyl-tRNA synthetase, Cell proliferation-inducing gene 32 protein, Glutamatyl-prolyl-tRNA synthetase |
| 2 | B (A) | 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine | non-polymer | 429.4 | 1 | Chemie (8X1) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 1003 - 1512 (UniProt: P07814)
| PDB | External Database | Details |
|---|---|---|
| Met 994 | - | expression tag |
| His 995 | - | expression tag |
| His 996 | - | expression tag |
| His 997 | - | expression tag |
| His 998 | - | expression tag |
| His 999 | - | expression tag |
| His 1000 | - | expression tag |
| Gly 1001 | - | expression tag |
| Ser 1002 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59063.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 494.8 | |
| All* | Total formula weight | 59558.3 |
