5V4N

Structure of HLA-DR1 with bound alpha3(135-145) peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	HLA-DRA1	polymer	189	21919.6	2	UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB	Homo sapiens (Human)	MHC class II antigen DRA
2	C, F	alpha3(135-145)-HLA-DRB1*01:01	polymer	216	24609.4	2	UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB	Homo sapiens (Human)	MHC class II antigen DRB1*1,DR1,MHC class II antigen DRB1*1,DR1,MHC class II antigen DRB1*1,DR1, chimeric construct,MHC class II antigen DRB1*1,DR1, chimeric construct
3	A, D, F	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, D: 1 - 181 (UniProt: P01903)

PDB	External Database	Details
Thr 182	-	expression tag
Ser 183	-	expression tag
Gly 184	-	expression tag
Asp 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Lys 189	-	expression tag

C, F: 0 - 10 (PDB: 5V4N)

PDB	External Database	Details
Gly 11	-	linker
Ser 12	-	linker
Gly 237	-	linker
Gly 238	-	linker
Ser 239	-	linker
Ile 240	-	linker
Glu 241	-	linker
Gly 242	-	linker
Arg 243	-	linker
Gly 244	-	linker
Gly 245	-	linker
Ser 246	-	linker
Gly 247	-	linker
Ala 248	-	linker

C, F: 249 - 439 (UniProt: P04229)

PDB	External Database	Details
Ser 249	Ala 29	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	93058.0
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	93721.6

*Water molecules are not included.