5V42
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Polyketide synthase Pks13 (Termination polyketide synthase) | polymer | 286 | 31777.7 | 2 | UniProt (A0A0T9CRX1) Pfam (PF00975) UniProt (by SIFTS) (I6X8D2) In PDB | Mycobacterium tuberculosis | |
| 2 | A, B | ethyl 5-hydroxy-2-phenyl-4-(pyrrolidin-1-ylmethyl)-1-benzofuran-3-carboxylate | non-polymer | 365.4 | 2 | Chemie (I66) | |||
| 3 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B: 1451 - 1733 (UniProt: A0A0T9CRX1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1448 | - | expression tag |
| Asn 1449 | - | expression tag |
| Ala 1450 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63555.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 730.8 | |
| All* | Total formula weight | 64286.3 |
