5V1B
Structure of PHD1 in complex with 1,2,4-Triazolo-[1,5-a]pyridine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Egl nine homolog 2 | polymer | 240 | 26565.4 | 1 | UniProt (Q96KS0) Pfam (PF13640) In PDB | Homo sapiens (Human) | Estrogen-induced tag 6,HPH-3,Hypoxia-inducible factor prolyl hydroxylase 1,HPH-1,Prolyl hydroxylase domain-containing protein 1,PHD1 |
2 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
4 | A | 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile | non-polymer | 220.2 | 1 | Chemie (8UY) | |||
5 | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 167 - 403 (UniProt: Q96KS0)
PDB | External Database | Details |
---|---|---|
Gly 164 | - | expression tag |
Gly 165 | - | expression tag |
Ser 166 | - | expression tag |
Val 194 | Lys 194 | conflict |
Lys 275 | Val 275 | conflict |
Asp 378 | Lys 378 | conflict |
Arg 382 | Ala 382 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26565.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 468.2 | |
All* | Total formula weight | 27033.6 |