5V0T

Crystal structure of an alpha,alpha-trehalose-phosphate synthase (UDP-forming) from Burkholderia xenovorans in complex with glucose-6-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)	polymer	494	55180.9	8	UniProt (Q13W28) Pfam (PF00982)	Burkholderia xenovorans (strain LB400)	Osmoregulatory trehalose synthesis protein A,Trehalose-6-phosphate synthase
2	CC, EB, I, MA, PB... (H, E, A, C, F...)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	8	Chemie (UDP)
3	DC, FB, J, NA, QB... (H, E, A, C, F...)	6-O-phosphono-alpha-D-glucopyranose	non-polymer		260.1	8	Chemie (G6P)
4	AC, EC, FC, HB, K... (G, H, E, A, B...)	1,2-ETHANEDIOL	non-polymer		62.1	15	Chemie (EDO)
5	AA, BA, BC, CA, DA... (B, G, H, E, A...)	ACETATE ION	non-polymer		59.0	15	Chemie (ACT)
6	EA, JB, O, RA, UB (B, E, A, C, F)	OXALIC ACID	non-polymer		90.0	5	Chemie (OXD)
7	AB, BB, CB, DB, FA... (D, B, H, E, A...)	FORMIC ACID	non-polymer		46.0	27	Chemie (FMT)
8	GB (E)	D(-)-TARTARIC ACID	non-polymer		150.1	1	Chemie (TAR)
9	JC, KC, LC, MC, NC... (A, B, C, D, E...)	water	water		18.0	2850	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 9 - 494 (UniProt: Q13W28)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	441446.8
Non-Polymers*	Number of molecules	79
	Total formula weight	8974.0
All*	Total formula weight	450420.8

*Water molecules are not included.