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5V0Q

Original engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 49 point mutations relative to wild-type I-OnuI

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
I-OnuI_e-vHIVInt_v1polymer30035076.31synthetic construct
2B
(B)
DNA (26-MER)polymer268036.21synthetic construct
3C
(C)
DNA (26-MER)polymer267938.11synthetic construct
4D, E
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
5F, G, H
(A, B, C)
waterwater18.063Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight51050.7
Non-Polymers*Number of molecules2
Total formula weight80.2
All*Total formula weight51130.8
*Water molecules are not included.

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PDB entries from 2025-06-25

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