5V0Q

Original engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 49 point mutations relative to wild-type I-OnuI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	I-OnuI_e-vHIVInt_v1	polymer	300	35076.3	1		synthetic construct
2	B	DNA (26-MER)	polymer	26	8036.2	1		synthetic construct
3	C	DNA (26-MER)	polymer	26	7938.1	1		synthetic construct
4	A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5		water	water		18.0	63	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	51050.7
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	51130.8

*Water molecules are not included.