5V0N
BACE1 in complex with inhibitor 5g
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Beta-secretase 1 | polymer | 441 | 48838.9 | 3 | UniProt (P56817) Pfam (PF00026) In PDB | Homo sapiens (Human) | Aspartyl protease 2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2 |
| 2 | A, B, C | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 3 | A, B, C | N-{(1S,2S)-1-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-hydroxy-3-phenylpropan-2-yl}-7-ethyl-1,3,3-trimethyl-2,2-dioxo-1,2,3,4-tetrahydro-2lambda~6~-[1,2,5]thiadiazepino[3,4,5-hi]indole-9-carboxamide | non-polymer | 657.8 | 3 | Chemie (8W4) | |||
| 4 | A, B | UREA | non-polymer | 60.1 | 2 | Chemie (URE) | |||
| 5 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 685 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 146516.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3242.4 | |
| All* | Total formula weight | 149759.1 |
