Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ARG235 |
| A | SER327 |
| A | SER328 |
| A | HOH502 |
| A | HOH565 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | HOH555 |
| A | HOH635 |
| A | PHE47 |
| A | LYS107 |
| A | HOH503 |
| A | HOH507 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ARG96 |
| A | GLU134 |
| A | HOH511 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue 8W4 A 404 |
| Chain | Residue |
| A | GLY11 |
| A | LEU30 |
| A | ASP32 |
| A | GLY34 |
| A | SER35 |
| A | TYR71 |
| A | THR72 |
| A | GLN73 |
| A | ILE126 |
| A | TYR198 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | ASN233 |
| A | ARG235 |
| A | SER325 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue URE A 405 |
| Chain | Residue |
| A | ARG307 |
| A | LYS321 |
| A | HOH522 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | ARG235 |
| B | GLN326 |
| B | SER327 |
| B | SER328 |
| B | HOH502 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | ARG96 |
| B | ALA97 |
| B | ASN98 |
| B | GLU134 |
| B | HOH528 |
| B | HOH568 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | ARG50 |
| B | TYR51 |
| B | GLN53 |
| B | HOH508 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | ASN293 |
| B | LEU377 |
| B | HOH526 |
| C | ARG205 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| B | ARG205 |
| B | VAL375 |
| B | THR376 |
| B | HOH560 |
| C | THR292 |
| C | ASP378 |
| C | HOH539 |
| site_id | AD2 |
| Number of Residues | 15 |
| Details | binding site for residue 8W4 B 406 |
| Chain | Residue |
| B | ASP32 |
| B | GLY34 |
| B | SER35 |
| B | TYR71 |
| B | THR72 |
| B | GLN73 |
| B | ILE126 |
| B | TYR198 |
| B | ASP228 |
| B | GLY230 |
| B | THR231 |
| B | THR232 |
| B | ASN233 |
| B | ARG235 |
| B | SER325 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue URE B 407 |
| Chain | Residue |
| B | GLU219 |
| B | TYR222 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 401 |
| Chain | Residue |
| C | VAL3 |
| C | GLN153 |
| C | HOH526 |
| C | HOH540 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 402 |
| Chain | Residue |
| B | GLU371 |
| C | ASN293 |
| C | GLN294 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 403 |
| Chain | Residue |
| C | ARG96 |
| C | ALA97 |
| C | ASN98 |
| C | GLU134 |
| C | HOH514 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 404 |
| Chain | Residue |
| C | ARG61 |
| C | HOH536 |
| site_id | AD8 |
| Number of Residues | 16 |
| Details | binding site for residue 8W4 C 405 |
| Chain | Residue |
| C | TYR198 |
| C | ASP228 |
| C | GLY230 |
| C | THR231 |
| C | THR232 |
| C | ASN233 |
| C | ARG235 |
| C | SER325 |
| C | GLY11 |
| C | ASP32 |
| C | GLY34 |
| C | SER35 |
| C | TYR71 |
| C | THR72 |
| C | GLN73 |
| C | ILE126 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP228 | |
| B | ASP32 | |
| B | ASP228 | |
| C | ASP32 | |
| C | ASP228 | |
| Chain | Residue | Details |
| A | LYS65 | |
| B | LYS218 | |
| B | LYS224 | |
| B | LYS238 | |
| B | LYS239 | |
| B | LYS246 | |
| C | LYS65 | |
| C | LYS214 | |
| C | LYS218 | |
| C | LYS224 | |
| C | LYS238 | |
| A | LYS214 | |
| C | LYS239 | |
| C | LYS246 | |
| A | LYS218 | |
| A | LYS224 | |
| A | LYS238 | |
| A | LYS239 | |
| A | LYS246 | |
| B | LYS65 | |
| B | LYS214 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN92 | |
| C | ASN111 | |
| C | ASN162 | |
| C | ASN293 | |
| A | ASN111 | |
| A | ASN162 | |
| A | ASN293 | |
| B | ASN92 | |
| B | ASN111 | |
| B | ASN162 | |
| B | ASN293 | |
| C | ASN92 | |
