5UZS
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Inosine-5'-monophosphate dehydrogenase | polymer | 363 | 38482.3 | 4 | UniProt (A0A0H2YRZ7) Pfam (PF00478) In PDB | Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) | IMPDH |
2 | A, B, C, D | INOSINIC ACID | non-polymer | 348.2 | 4 | Chemie (IMP) | |||
3 | A, B, C, D | 3-(2-{[(4-chlorophenyl)carbamoyl]amino}propan-2-yl)-N-hydroxybenzene-1-carboximidamide | non-polymer | 346.8 | 4 | Chemie (8L4) | |||
4 | A, B, C | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 5 | Chemie (PGE) | |||
5 | D, A, B, C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
6 | B, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
7 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
8 | B, C | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
9 | D | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
10 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 88 (UniProt: A0A0H2YRZ7)
A, B, C, D: 216 - 484 (UniProt: A0A0H2YRZ7)
PDB | External Database | Details |
---|---|---|
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 89 | - | linker |
Gly 90 | - | linker |
Gly 91 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 153929.2 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 4588.5 | |
All* | Total formula weight | 158517.7 |