Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003938 | molecular_function | IMP dehydrogenase activity |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0003938 | molecular_function | IMP dehydrogenase activity |
| D | 0006164 | biological_process | purine nucleotide biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue IMP A 500 |
| Chain | Residue |
| A | ALA47 |
| A | GLY338 |
| A | MET358 |
| A | GLY359 |
| A | SER360 |
| A | TYR383 |
| A | GLY385 |
| A | MET386 |
| A | GLY387 |
| A | GLU411 |
| A | GLY412 |
| A | MET49 |
| A | 8L4501 |
| A | HOH608 |
| A | ASN275 |
| A | GLY300 |
| A | SER301 |
| A | ILE302 |
| A | CYS303 |
| A | ASP336 |
| A | GLY337 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue 8L4 A 501 |
| Chain | Residue |
| A | ALA248 |
| A | THR305 |
| A | GLY387 |
| A | VAL409 |
| A | GLU411 |
| A | IMP500 |
| C | PRO25 |
| C | SER436 |
| C | GLY439 |
| C | TYR440 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue PGE A 502 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PGE A 503 |
| Chain | Residue |
| A | ASN41 |
| A | ALA62 |
| A | ARG63 |
| A | GLY65 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 504 |
| Chain | Residue |
| A | TYR428 |
| A | ILE431 |
| A | LYS435 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | binding site for residue IMP B 500 |
| Chain | Residue |
| B | ALA47 |
| B | MET49 |
| B | GLY300 |
| B | SER301 |
| B | ILE302 |
| B | CYS303 |
| B | ASP336 |
| B | GLY337 |
| B | GLY338 |
| B | MET358 |
| B | GLY359 |
| B | SER360 |
| B | TYR383 |
| B | GLY385 |
| B | MET386 |
| B | GLY387 |
| B | GLU411 |
| B | 8L4501 |
| B | HOH606 |
| B | HOH617 |
| B | HOH618 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue 8L4 B 501 |
| Chain | Residue |
| A | PRO25 |
| A | SER436 |
| A | GLY439 |
| A | TYR440 |
| B | ALA248 |
| B | THR305 |
| B | MET386 |
| B | GLY387 |
| B | MET392 |
| B | VAL409 |
| B | GLU411 |
| B | IMP500 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 502 |
| Chain | Residue |
| B | ASN41 |
| B | ARG63 |
| B | GLU64 |
| B | GLY65 |
| B | HOH601 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ILE4 |
| B | LYS6 |
| B | THR7 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue PGE B 504 |
| Chain | Residue |
| B | LYS6 |
| B | THR317 |
| B | ASP321 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 505 |
| Chain | Residue |
| B | GLU366 |
| B | GLU366 |
| B | HIS422 |
| B | HIS422 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue K B 506 |
| Chain | Residue |
| B | GLU465 |
| B | SER466 |
| B | HIS467 |
| D | GLY298 |
| D | GLY300 |
| D | CYS303 |
| site_id | AD4 |
| Number of Residues | 22 |
| Details | binding site for residue IMP C 500 |
| Chain | Residue |
| C | CYS303 |
| C | ASP336 |
| C | GLY337 |
| C | GLY338 |
| C | GLY359 |
| C | SER360 |
| C | TYR383 |
| C | GLY385 |
| C | MET386 |
| C | GLY387 |
| C | GLU411 |
| C | GLY412 |
| C | 8L4501 |
| C | HOH605 |
| C | HOH607 |
| C | HOH610 |
| C | HOH631 |
| C | ALA47 |
| C | MET49 |
| C | GLY300 |
| C | SER301 |
| C | ILE302 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for residue 8L4 C 501 |
| Chain | Residue |
| C | ALA248 |
| C | THR305 |
| C | MET386 |
| C | GLY387 |
| C | PHE408 |
| C | VAL409 |
| C | GLU411 |
| C | IMP500 |
| C | HOH602 |
| D | PRO25 |
| D | SER436 |
| D | GLY439 |
| D | TYR440 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG C 502 |
| Chain | Residue |
| C | ASN41 |
| C | ALA62 |
| C | ARG63 |
| C | GLU64 |
| C | GLY65 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue PGE C 503 |
| Chain | Residue |
| C | LYS6 |
| C | ASP321 |
| C | HOH608 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 504 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue PGE C 505 |
| Chain | Residue |
| A | LYS407 |
| A | PHE408 |
| A | HOH615 |
| C | TYR428 |
| C | ILE431 |
| C | GLY432 |
| C | LYS435 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue K C 506 |
| Chain | Residue |
| C | GLY298 |
| C | GLY300 |
| C | CYS303 |
| D | GLU465 |
| D | SER466 |
| D | HIS467 |
| site_id | AE2 |
| Number of Residues | 23 |
| Details | binding site for residue IMP D 500 |
| Chain | Residue |
| D | ALA47 |
| D | ASN275 |
| D | GLY300 |
| D | SER301 |
| D | ILE302 |
| D | CYS303 |
| D | ASP336 |
| D | GLY337 |
| D | GLY338 |
| D | MET358 |
| D | GLY359 |
| D | SER360 |
| D | TYR383 |
| D | GLY385 |
| D | MET386 |
| D | GLY387 |
| D | GLU411 |
| D | GLY412 |
| D | 8L4501 |
| D | HOH611 |
| D | HOH612 |
| D | HOH615 |
| D | HOH626 |
| site_id | AE3 |
| Number of Residues | 12 |
| Details | binding site for residue 8L4 D 501 |
| Chain | Residue |
| B | PRO25 |
| B | SER436 |
| B | GLY439 |
| B | TYR440 |
| D | ALA248 |
| D | THR305 |
| D | MET386 |
| D | GLY387 |
| D | VAL409 |
| D | GLU411 |
| D | IMP500 |
| D | HOH606 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue PEG D 502 |
| Chain | Residue |
| C | PHE408 |
| D | TYR428 |
| D | GLY432 |
| D | LYS435 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG D 503 |
| Chain | Residue |
| D | ILE4 |
| D | LYS6 |
| D | THR7 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG D 504 |
| Chain | Residue |
| D | ASN41 |
| D | ARG63 |
| D | GLU64 |
| D | GLY65 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 D 505 |
| Chain | Residue |
| B | VAL17 |
| D | LEU5 |
| D | LYS6 |
| D | THR317 |
| D | ASP321 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL293-THR305 | |
