5UZC
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P221
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Inosine-5'-monophosphate dehydrogenase | polymer | 363 | 38441.3 | 4 | UniProt (A0A0H2YRZ7) | Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) | IMPDH |
| 2 | E, J, N, R (A, B, C, D) | INOSINIC ACID | non-polymer | 348.2 | 4 | Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734) | |||
| 3 | F, K, O, S (A, B, C, D) | N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-beta-D-xylofuranosylamine | non-polymer | 476.0 | 4 | Chemie (8N1) PubChem (124220275) PubChem (124219491) PubChem (146637049) PubChem (146637071) | |||
| 4 | G, L, T (A, B, D) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 5 | H, Q, U (A, C, D) | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
| 6 | I, M (A, B) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) PubChem (284) | |||
| 7 | P (C) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) PubChem (7870) PubChem (5288834) PubChem (5288845) | |||
| 8 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 88 (UniProt: A0A0H2YRZ7)
A, B, C, D: 89 - 484 (UniProt: A0A0H2YRZ7)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 89 | Lys 213 | linker |
| Gly 90 | Gly 214 | linker |
| Gly 91 | Arg 215 | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 153765.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 4041.6 | |
| All* | Total formula weight | 157806.7 |
