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5UXD

Crystal structure of macrolide 2'-phosphotransferase MphH from Brachybacterium faecium in complex with azithromycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Macrolide 2'-phosphotransferase MphHpolymer30032213.12UniProt (C7MEP1)
Pfam (PF01636)
Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860)
2C, I, J
(A, B)
AZITHROMYCINnon-polymer749.03Chemie (ZIT)
3D, K
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
4E, F, G, H, L...
(A, B)
CHLORIDE IONnon-polymer35.56Chemie (CL)
5N, O
(A, B)
waterwater18.01247Chemie (HOH)
Sequence modifications
A, B: 1 - 298 (UniProt: C7MEP1)
PDBExternal DatabaseDetails
Gln -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight64426.3
Non-Polymers*Number of molecules11
Total formula weight2651.8
All*Total formula weight67078.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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