5UWN
Matrix metalloproteinase-13 complexed with selective inhibitor compound 10d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Collagenase 3 | polymer | 172 | 19366.6 | 5 | UniProt (P45452) Pfam (PF00413) | Homo sapiens (Human) | Matrix metalloproteinase-13,MMP-13 |
| 2 | AA, BA, F, G, KA... (D, A, E, B, C) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 3 | CA, DA, H, I, MA... (D, A, E, B, C) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 4 | EA, J, OA, Q, X (D, A, E, B, C) | N-(2-aminoethyl)-4'-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)-[1,1'-biphenyl]-4-sulfonami de | non-polymer | 456.6 | 5 | Chemie (8O7) | |||
| 5 | FA, GA, HA, IA, JA... (D, A, E, B, C) | SULFATE ION | non-polymer | 96.1 | 14 | Chemie (SO4) |
Sequence modifications
A, B, C, D, E: 104 - 274 (UniProt: P45452)
| PDB | External Database | Details |
|---|---|---|
| Met 103 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96832.9 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 4682.7 | |
| All* | Total formula weight | 101515.5 |
