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5UVG

Crystal structure of the human neutral sphingomyelinase 2 (nSMase2) catalytic domain with insertion deleted and calcium bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sphingomyelin phosphodiesterase 3,Sphingomyelin phosphodiesterase 3polymer37141348.51UniProt (Q9NY59)
Pfam (PF03372)
Homo sapiens (Human)Neutral sphingomyelinase 2,nSMase2,Neutral sphingomyelinase II,Neutral sphingomyelinase 2,nSMase2,Neutral sphingomyelinase II
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
waterwater18.0212Chemie (HOH)
Sequence modifications
A: 117 - 174 (UniProt: Q9NY59)
PDBExternal DatabaseDetails
Ser 116-expression tag
A: 340 - 651 (UniProt: Q9NY59)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41348.5
Non-Polymers*Number of molecules1
Total formula weight40.1
All*Total formula weight41388.5
*Water molecules are not included.

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PDB entries from 2025-12-17

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