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5UU1

Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to BI-D1870

Replaces:  5TKX
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase VRK2polymer32436788.21UniProt (Q86Y07)
Pfam (PF00069)
Homo sapiens (Human)Vaccinia-related kinase 2
2B
(A)
(7S)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-onenon-polymer391.41Chemie (7DZ)
3C
(A)
waterwater18.0137Chemie (HOH)
Sequence modifications
A: 14 - 335 (UniProt: Q86Y07)
PDBExternal DatabaseDetails
Ser 12-expression tag
Met 13-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36788.2
Non-Polymers*Number of molecules1
Total formula weight391.4
All*Total formula weight37179.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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