5UTU
2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Adenosylhomocysteinase | polymer | 498 | 56200.7 | 8 | UniProt (Q5CPH1) Pfam (PF05221) Pfam (PF00670) | Cryptosporidium parvum (strain Iowa II) | |
| 2 | EA, HB, I, LA, Q... (D, H, A, E, B...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 3 | FA, IB, J, MA, R... (D, H, A, E, B...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 8 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | AB, BB, GA, K, KB... (G, D, A, H, E...) | CHLORIDE ION | non-polymer | 35.5 | 11 | Chemie (CL) PubChem (312) | |||
| 5 | AA, BA, CA, CB, DA... (C, G, D, A, H...) | SULFATE ION | non-polymer | 96.1 | 22 | Chemie (SO4) | |||
| 6 | NB, P, W (H, A, B) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 3 | Chemie (P33) PubChem (79718) | |||
| 7 | KA, XA (D, F) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) PubChem (17472) | |||
| 8 | JB, TA (H, F) | ADENOSINE | non-polymer | 267.2 | 2 | Chemie (ADN) | |||
| 9 | FB, GB (G) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) PubChem (8117) | |||
| 10 | OB, PB, QB, RB, SB... (A, B, C, D, E...) | water | water | 18.0 | 931 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 495 (UniProt: Q5CPH1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 449605.4 | |
| Non-Polymers* | Number of molecules | 58 |
| Total formula weight | 13176.6 | |
| All* | Total formula weight | 462782.0 |
