5UTU

2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Adenosylhomocysteinase	polymer	498	56200.7	8	UniProt (Q5CPH1) Pfam (PF05221) Pfam (PF00670) In PDB	Cryptosporidium parvum (strain Iowa II)
2	D, H, A, E, B...	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)
3	D, H, A, E, B...	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	8	Chemie (SAH)
4	G, D, A, H, E...	CHLORIDE ION	non-polymer		35.5	11	Chemie (CL)
5	C, G, D, A, H...	SULFATE ION	non-polymer		96.1	22	Chemie (SO4)
6	H, A, B	3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL	non-polymer		326.4	3	Chemie (P33)
7	D, F	HEXAETHYLENE GLYCOL	non-polymer		282.3	2	Chemie (P6G)
8	H, F	ADENOSINE	non-polymer		267.2	2	Chemie (ADN)
9	G	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
10		water	water		18.0	931	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 495 (UniProt: Q5CPH1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	449605.4
Non-Polymers*	Number of molecules	58
	Total formula weight	13176.6
All*	Total formula weight	462782.0

*Water molecules are not included.