5UTK
Crystal structure of the membrane proximal three fibronectin type III (FNIII) domains of Tie2 (Tie2[FNIIIa-c])
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Angiopoietin-1 receptor | polymer | 304 | 34137.0 | 2 | UniProt (Q02763) Pfam (PF00041) In PDB | Homo sapiens (Human) | Endothelial tyrosine kinase,Tunica interna endothelial cell kinase,Tyrosine kinase with Ig and EGF homology domains-2,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,hTIE2,p140 TEK |
| 2 | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A, B: 442 - 741 (UniProt: Q02763)
| PDB | External Database | Details |
|---|---|---|
| Gly 438 | - | expression tag |
| Ser 439 | - | expression tag |
| Gly 440 | - | expression tag |
| Ser 441 | - | expression tag |
| Mse 612 | Val 569 | engineered mutation |
| Mse 656 | Val 613 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68274.0 | |
| All* | Total formula weight | 68274.0 |
