5USR
Crystal structure of human NFS1-ISD11 in complex with E. coli acyl-carrier protein at 3.09 angstroms
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | Cysteine desulfurase, mitochondrial | polymer | 426 | 47623.3 | 4 | UniProt (Q9Y697) Pfam (PF00266) In PDB | Homo sapiens (Human) | |
2 | B, D, F, H | LYR motif-containing protein 4 | polymer | 91 | 10763.5 | 4 | UniProt (Q9HD34) Pfam (PF05347) In PDB | Homo sapiens (Human) | |
3 | I, J, K, L | Acyl carrier protein | polymer | 78 | 8645.5 | 4 | UniProt (P0A6A8) Pfam (PF00550) In PDB | Escherichia coli (strain K12) | ACP,Cytosolic-activating factor,CAF,Fatty acid synthase acyl carrier protein |
4 | I, J, K, L | S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate | non-polymer | 540.7 | 4 | Chemie (8Q1) |
Sequence modifications
A, C, E, G: 56 - 457 (UniProt: Q9Y697)
B, D, F, H: 1 - 91 (UniProt: Q9HD34)
PDB | External Database | Details |
---|---|---|
Met 32 | - | initiating methionine |
Gly 33 | - | expression tag |
Ser 34 | - | expression tag |
Ser 35 | - | expression tag |
His 36 | - | expression tag |
His 37 | - | expression tag |
His 38 | - | expression tag |
His 39 | - | expression tag |
His 40 | - | expression tag |
His 41 | - | expression tag |
Ser 42 | - | expression tag |
Ser 43 | - | expression tag |
Gly 44 | - | expression tag |
Leu 45 | - | expression tag |
Val 46 | - | expression tag |
Pro 47 | - | expression tag |
Arg 48 | - | expression tag |
Gly 49 | - | expression tag |
Ser 50 | - | expression tag |
His 51 | - | expression tag |
Met 52 | - | expression tag |
Leu 53 | - | expression tag |
Glu 54 | - | expression tag |
Met 55 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 11 | Ser 11 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 268129.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2162.6 | |
All* | Total formula weight | 270291.6 |