5USQ
ALK-5 kinase inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TGF-beta receptor type-1 | polymer | 299 | 34265.4 | 1 | UniProt (P36897) Pfam (PF00069) | Homo sapiens (Human) | TGFR-1,Activin A receptor type II-like protein kinase of 53kD,Activin receptor-like kinase 5,ALK5,Serine/threonine-protein kinase receptor R4,SKR4,TGF-beta type I receptor,Transforming growth factor-beta receptor type I,TbetaR-I |
| 2 | B (A) | N-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-2-[(piperidin-4-yl)methyl]-2H-pyrazolo[4,3-b]pyridin-7-amine | non-polymer | 436.9 | 1 | Chemie (8LY) | |||
| 3 | C (A) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34265.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 436.9 | |
| All* | Total formula weight | 34702.3 |
