5URZ

Crystal structure of Frizzled 5 CRD in complex with BOG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Frizzled-5	polymer	146	16769.1	2	UniProt (Q13467) Pfam (PF01392)	Homo sapiens (Human)	hFz5,FzE5
2	C (C)	alpha-L-fucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		513.5	1	In PDB GlyTouCan (G99664XK)
3	D (B)	octyl beta-D-glucopyranoside	non-polymer		292.4	1	Chemie (BOG)
4	E, F (A, B)	water	water		18.0	97	Chemie (HOH)

Sequence modifications

A, B: 3 - 130 (UniProt: Q13467)

PDB	External Database	Details
Ala -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Gly -5	-	expression tag
Glu -4	-	expression tag
Asn -3	-	expression tag
Leu -2	-	expression tag
Tyr -1	-	expression tag
Phe 0	-	expression tag
Gln 1	-	expression tag
Gly 2	-	expression tag
Glu 126	Asn 151	conflict
Gly 131	-	expression tag
Asn 132	-	expression tag
Ser 133	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33538.2
Branched	Number of molecules	1
	Total formula weight	513.5
Non-Polymers*	Number of molecules	1
	Total formula weight	292.4
All*	Total formula weight	34344.1

*Water molecules are not included.