5URC
Design, Synthesis, Functional and Biological Evaluation of Ether and Ester Derivatives of the Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (Human) | Alpha-globin,Hemoglobin alpha chain |
| 2 | B, D (B, D) | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (Human) | Beta-globin,Hemoglobin beta chain |
| 3 | E, H, J, M (A, B, C, D) | CARBON MONOXIDE | non-polymer | 28.0 | 4 | Chemie (CMO) | |||
| 4 | F, I, K, N (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 5 | G (A) | (5-formylfuran-2-yl)methyl acetate | non-polymer | 168.1 | 1 | Chemie (8MV) | |||
| 6 | L (C) | 5-HYDROXYMETHYL-FURFURAL | non-polymer | 126.1 | 1 | Chemie (FUX) | |||
| 7 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 1234 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2872.2 | |
| All* | Total formula weight | 64953.3 |
