5UPY
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Listeria Monocytogenes in the complex with IMP and Q21
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inosine-5'-monophosphate dehydrogenase | polymer | 364 | 38455.9 | 1 | UniProt (Q926Y9) Pfam (PF00478) | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | IMPDH |
| 2 | B (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) | |||
| 3 | C (A) | (2S)-2-(naphthalen-1-yloxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]propanamide | non-polymer | 409.4 | 1 | Chemie (Q21) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H, I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | K (A) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A: 1 - 91 (UniProt: Q926Y9)
A: 221 - 488 (UniProt: Q926Y9)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 92 | - | linker |
| Gly 93 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38455.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1255.6 | |
| All* | Total formula weight | 39711.5 |
