Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue IMP A 500 |
| Chain | Residue |
| A | ALA49 |
| A | GLY364 |
| A | SER365 |
| A | TYR388 |
| A | GLY390 |
| A | MET391 |
| A | GLY392 |
| A | GLU416 |
| A | GLY417 |
| A | Q21501 |
| A | HOH623 |
| A | MET51 |
| A | HOH648 |
| A | HOH649 |
| A | HOH667 |
| A | HOH676 |
| A | GLY305 |
| A | SER306 |
| A | ILE307 |
| A | CYS308 |
| A | ASP341 |
| A | GLY343 |
| A | MET362 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue Q21 A 501 |
| Chain | Residue |
| A | SER23 |
| A | VAL25 |
| A | LEU26 |
| A | PRO27 |
| A | ALA253 |
| A | SER257 |
| A | THR310 |
| A | MET391 |
| A | GLY392 |
| A | VAL414 |
| A | GLU416 |
| A | SER441 |
| A | TYR445 |
| A | IMP500 |
| A | HOH686 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | PHE271 |
| A | ASP273 |
| A | VAL274 |
| A | HOH671 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | THR322 |
| A | HOH619 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | LEU11 |
| A | ASP15 |
| A | ARG462 |
| A | MET463 |
| A | THR464 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | ALA37 |
| A | PRO38 |
| A | SER39 |
| A | ASP273 |
| A | VAL274 |
| A | ASP296 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 506 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLU35 |
| A | GLY335 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | VAL245 |
| A | ASP246 |
| A | HOH671 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL298-THR310 | |
