5UPL

CDC42 binds PAK4 via an extended GTPase-effector inteface - 2 peptide: PAK4FL, CDC42 - UNREFINED

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Serine/threonine-protein kinase PAK 4	polymer	453	51099.7	1	UniProt (O96013) Pfam (PF00786) Pfam (PF00069) In PDB	Homo sapiens (Human)	p21-activated kinase 4,PAK-4
2	B	Cell division control protein 42 homolog	polymer	185	20716.7	1	UniProt (P60953) Pfam (PF00071) In PDB	Homo sapiens (Human)	G25K GTP-binding protein

Sequence modifications

A: 167 - 591 (UniProt: O96013)

PDB	External Database	Details
Met 139	-	initiating methionine
Gly 140	-	expression tag
Ser 141	-	expression tag
Ser 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
Ser 149	-	expression tag
Ser 150	-	expression tag
Gly 151	-	expression tag
Leu 152	-	expression tag
Val 153	-	expression tag
Pro 154	-	expression tag
Arg 155	-	expression tag
Gly 156	-	expression tag
Ser 157	-	expression tag
His 158	-	expression tag
Met 159	-	expression tag
Glu 160	-	expression tag
Asn 161	-	expression tag
Leu 162	-	expression tag
Tyr 163	-	expression tag
Phe 164	-	expression tag
Gln 165	-	expression tag
Gly 166	-	expression tag

B: 1 - 177 (UniProt: P60953)

PDB	External Database	Details
Leu 178	-	expression tag
Glu 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71816.4
All*	Total formula weight	71816.4

*Water molecules are not included.