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5UP0

Crystal structure of human PDE1B catalytic domain in complex with inhibitor 3 (6-(4-chlorobenzyl)-8,9,10,11-tetrahydrobenzo[4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Bpolymer36141279.01UniProt (Q01064)
Pfam (PF00233)
In PDB
Homo sapiens (Human)Cam-PDE 1B,63 kDa Cam-PDE
2AZINC IONnon-polymer65.41Chemie (ZN)
3AMAGNESIUM IONnon-polymer24.31Chemie (MG)
4A6-[(4-chlorophenyl)methyl]-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-onenon-polymer370.91Chemie (8HP)
5waterwater18.0105Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41279.0
Non-Polymers*Number of molecules3
Total formula weight460.6
All*Total formula weight41739.6
*Water molecules are not included.

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PDB entries from 2024-08-07

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