5UL0
S. CEREVISIAE CYP51 COMPLEXED WITH VT-1161
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lanosterol 14-alpha demethylase | polymer | 528 | 60587.7 | 1 | UniProt (A6ZSR0) Pfam (PF00067) | Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) | |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol | non-polymer | 527.4 | 1 | Chemie (VT1) | |||
| 4 | D (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 5 | E (A) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A: 7 - 530 (UniProt: A6ZSR0)
| PDB | External Database | Details |
|---|---|---|
| Gly 531 | - | expression tag |
| Gly 532 | - | expression tag |
| Arg 533 | - | expression tag |
| His 534 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60587.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1382.2 | |
| All* | Total formula weight | 61969.9 |
