5UJT
Crystal structure of human HLA-DQ8 in complex with insulin mimotope binding in register 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, D, G) | MHC class II antigen | polymer | 185 | 21138.5 | 3 | UniProt (Q5Y7C3) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B, E, H (B, E, H) | MHC class II HLA-DQ-beta-1 | polymer | 189 | 22246.0 | 3 | UniProt (O19707) Pfam (PF00969) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, F, I (C, F, I) | insulin mimotope | polymer | 16 | 1581.7 | 3 | Homo sapiens | ||
| 4 | J (J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB GlyTouCan (G26744ZJ) | |||
| 5 | K, L, M (A, D, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 645 | Chemie (HOH) |
Sequence modifications
A, D, G: -2 - 181 (UniProt: Q5Y7C3)
| PDB | External Database | Details |
|---|---|---|
| Cys 72 | Ile 98 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 134898.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 627.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 136189.9 |
