5UJJ
Crystal structure of human H130R tryptophanyl-tRNA synthetase in complex with TrpAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tryptophan--tRNA ligase, cytoplasmic | polymer | 484 | 54777.0 | 2 | UniProt (P23381) Pfam (PF00458) Pfam (PF00579) | Homo sapiens (Human) | Interferon-induced protein 53,IFP53,Tryptophanyl-tRNA synthetase,hWRS |
| 2 | C, F (A, B) | TRYPTOPHANYL-5'AMP | non-polymer | 533.4 | 2 | Chemie (TYM) | |||
| 3 | D, E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 471 (UniProt: P23381)
| PDB | External Database | Details |
|---|---|---|
| Arg 130 | His 130 | engineered mutation |
| Lys 472 | - | expression tag |
| Leu 473 | - | expression tag |
| Ala 474 | - | expression tag |
| Ala 475 | - | expression tag |
| Ala 476 | - | expression tag |
| Leu 477 | - | expression tag |
| Glu 478 | - | expression tag |
| His 479 | - | expression tag |
| His 480 | - | expression tag |
| His 481 | - | expression tag |
| His 482 | - | expression tag |
| His 483 | - | expression tag |
| His 484 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109554.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1139.8 | |
| All* | Total formula weight | 110693.8 |
