5UJJ

Crystal structure of human H130R tryptophanyl-tRNA synthetase in complex with TrpAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tryptophan--tRNA ligase, cytoplasmic	polymer	484	54777.0	2	UniProt (P23381) Pfam (PF00458) Pfam (PF00579) In PDB	Homo sapiens (Human)	Interferon-induced protein 53,IFP53,Tryptophanyl-tRNA synthetase,hWRS
2	A, B	TRYPTOPHANYL-5'AMP	non-polymer		533.4	2	Chemie (TYM)
3	A, B	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4		water	water		18.0	162	Chemie (HOH)

Sequence modifications

A, B: 1 - 471 (UniProt: P23381)

PDB	External Database	Details
Arg 130	His 130	engineered mutation
Lys 472	-	expression tag
Leu 473	-	expression tag
Ala 474	-	expression tag
Ala 475	-	expression tag
Ala 476	-	expression tag
Leu 477	-	expression tag
Glu 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag
His 482	-	expression tag
His 483	-	expression tag
His 484	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	109554.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1139.8
All*	Total formula weight	110693.8

*Water molecules are not included.