5UJI

Crystal structure of human T2-Tryptophanyl-tRNA synthetase with H130R mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tryptophan--tRNA ligase, cytoplasmic	polymer	388	44644.9	2	UniProt (P23381) Pfam (PF00579)	Homo sapiens (Human)	Interferon-induced protein 53,IFP53,Tryptophanyl-tRNA synthetase,hWRS

Sequence modifications

A, B: 97 - 471 (UniProt: P23381)

PDB	External Database	Details
Arg 130	His 89	engineered mutation
Lys 472	-	expression tag
Leu 473	-	expression tag
Ala 474	-	expression tag
Ala 475	-	expression tag
Ala 476	-	expression tag
Leu 477	-	expression tag
Glu 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag
His 482	-	expression tag
His 483	-	expression tag
His 484	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	89289.8
All*	Total formula weight	89289.8

*Water molecules are not included.