5UIH
structure of DHFR with bound phenformin and NADP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydrofolate reductase | polymer | 169 | 19076.4 | 1 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli | |
2 | A | N-(2-phenylethyl)imidodicarbonimidic diamide | non-polymer | 205.3 | 1 | Chemie (8CV) | |||
3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
5 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
7 | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
PDB | External Database | Details |
---|---|---|
Gly 160 | - | expression tag |
Gly 161 | - | expression tag |
Gly 162 | - | expression tag |
Gly 163 | - | expression tag |
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
His 167 | - | expression tag |
His 168 | - | expression tag |
His 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19076.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1111.9 | |
All* | Total formula weight | 20188.3 |