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5UGM

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Edaglitazone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27130997.02UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2C, D, F, G
(A, B)
(5R)-5-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}methyl)-1,3-thiazolidine-2,4-dionenon-polymer464.64Chemie (8A7)
3E, H
(A, B)
nonanoic acidnon-polymer158.22Chemie (KNA)
4I, J
(A, B)
waterwater18.0473Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61994.0
Non-Polymers*Number of molecules6
Total formula weight2174.7
All*Total formula weight64168.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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