Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 8A7 A 501 |
| Chain | Residue |
| A | PHE282 |
| A | HIS449 |
| A | LEU469 |
| A | TYR473 |
| A | KNA503 |
| A | HOH692 |
| A | CYS285 |
| A | SER289 |
| A | HIS323 |
| A | TYR327 |
| A | LEU330 |
| A | ILE341 |
| A | SER342 |
| A | MET364 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 8A7 A 502 |
| Chain | Residue |
| A | ILE267 |
| A | PRO269 |
| A | LEU270 |
| A | GLN271 |
| A | PHE287 |
| A | SER464 |
| A | HIS466 |
| A | PRO467 |
| A | HOH744 |
| B | VAL293 |
| B | THR297 |
| B | VAL315 |
| B | LEU468 |
| B | HOH647 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue KNA A 503 |
| Chain | Residue |
| A | PHE264 |
| A | HIS266 |
| A | ARG280 |
| A | GLN283 |
| A | PHE287 |
| A | SER342 |
| A | 8A7501 |
| A | HOH665 |
| A | HOH668 |
| A | HOH693 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue 8A7 B 501 |
| Chain | Residue |
| B | PHE264 |
| B | PHE282 |
| B | CYS285 |
| B | SER289 |
| B | HIS323 |
| B | TYR327 |
| B | LEU330 |
| B | ILE341 |
| B | SER342 |
| B | MET364 |
| B | LYS367 |
| B | HIS449 |
| B | LEU469 |
| B | TYR473 |
| B | KNA503 |
| B | HOH730 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue 8A7 B 502 |
| Chain | Residue |
| A | VAL293 |
| A | THR297 |
| A | VAL315 |
| A | LEU468 |
| A | ILE472 |
| A | HOH610 |
| A | HOH621 |
| B | PRO269 |
| B | LEU270 |
| B | GLN271 |
| B | PHE287 |
| B | SER464 |
| B | HIS466 |
| B | PRO467 |
| B | HOH758 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue KNA B 503 |
| Chain | Residue |
| B | PHE264 |
| B | LYS265 |
| B | HIS266 |
| B | ARG280 |
| B | GLN283 |
| B | 8A7501 |
| B | HOH628 |
| B | HOH669 |
| B | HOH689 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 530 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Motif: {"description":"9aaTAD","evidences":[{"source":"PubMed","id":"30468856","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9744270","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PRG","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36737649","evidenceCode":"ECO:0000269"}]} |
