5UGH
Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | S-adenosylmethionine synthase isoform type-2 | polymer | 397 | 43864.8 | 4 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB | Homo sapiens (Human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
2 | A, B, C | 2-(7-chloro-5-phenyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine | non-polymer | 350.8 | 4 | Chemie (8AJ) | |||
3 | water | water | 18.0 | 385 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 395 (UniProt: P31153)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 175459.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1403.4 | |
All* | Total formula weight | 176862.4 |