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5UFO

Structure of RORgt bound to

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANuclear receptor ROR-gammapolymer25830102.71UniProt (P51449)
Pfam (PF00104)
In PDB
Homo sapiens (Human)Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma
2A(S)-{4-chloro-2-methoxy-3-[4-(methylsulfonyl)phenyl]quinolin-6-yl}(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanolnon-polymer603.01Chemie (87J)
Sequence modifications
A: 265 - 507 (UniProt: P51449)
PDBExternal DatabaseDetails
Gly 250-expression tag
His 251-expression tag
His 252-expression tag
His 253-expression tag
His 254-expression tag
His 255-expression tag
His 256-expression tag
Gly 257-expression tag
Glu 258-expression tag
Asn 259-expression tag
Leu 260-expression tag
Tyr 261-expression tag
Phe 262-expression tag
Gln 263-expression tag
Gly 264-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30102.7
Non-Polymers*Number of molecules1
Total formula weight603.0
All*Total formula weight30705.7
*Water molecules are not included.

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PDB entries from 2024-04-24

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