5UFO
Structure of RORgt bound to
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 258 | 30102.7 | 1 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B (A) | (S)-{4-chloro-2-methoxy-3-[4-(methylsulfonyl)phenyl]quinolin-6-yl}(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol | non-polymer | 603.0 | 1 | Chemie (87J) |
Sequence modifications
A: 265 - 507 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
| His 254 | - | expression tag |
| His 255 | - | expression tag |
| His 256 | - | expression tag |
| Gly 257 | - | expression tag |
| Glu 258 | - | expression tag |
| Asn 259 | - | expression tag |
| Leu 260 | - | expression tag |
| Tyr 261 | - | expression tag |
| Phe 262 | - | expression tag |
| Gln 263 | - | expression tag |
| Gly 264 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30102.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 603.0 | |
| All* | Total formula weight | 30705.7 |






