5UFI

DCN1 bound to DI-591

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	DCN1-like protein 1	polymer	225	26251.9	4	UniProt (Q96GG9) Pfam (PF03556)	Homo sapiens (Human)	DCUN1 domain-containing protein 1,Defective in cullin neddylation protein 1-like protein 1,Squamous cell carcinoma-related oncogene
2	E, F, G, H (A, B, C, D)	N-[(1S)-1-cyclohexyl-2-{[3-(morpholin-4-yl)propanoyl]amino}ethyl]-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide	non-polymer		585.8	4	BIRD (PRD_002263) Chemie (8B1)
3	I, J, K, L (A, B, C, D)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

A, B, C, D: 58 - 259 (UniProt: Q96GG9)

PDB	External Database	Details
Met 35	-	initiating methionine
Ser 36	-	expression tag
Tyr 37	-	expression tag
Tyr 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
His 43	-	expression tag
His 44	-	expression tag
Leu 45	-	expression tag
Glu 46	-	expression tag
Ser 47	-	expression tag
Thr 48	-	expression tag
Ser 49	-	expression tag
Leu 50	-	expression tag
Tyr 51	-	expression tag
Lys 52	-	expression tag
Lys 53	-	expression tag
Ala 54	-	expression tag
Gly 55	-	expression tag
Thr 56	-	expression tag
Met 57	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	105007.5
Non-Polymers*	Number of molecules	4
	Total formula weight	2343.2
All*	Total formula weight	107350.7

*Water molecules are not included.