5U6G

Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, H...)	Retinol-binding protein 2	polymer	133	15584.4	10	UniProt (P50120) Pfam (PF00061)	Homo sapiens (Human)	Cellular retinol-binding protein II,CRBP-II
2	H, I (G, I)	Retinol-binding protein 2	polymer	133	15598.5	2	UniProt (P50120) Pfam (PF00061)	Homo sapiens (Human)	Cellular retinol-binding protein II,CRBP-II
3	M, N, O, P, Q... (A, B, C, D, H...)	RETINAL	non-polymer		284.4	11	Chemie (RET)
4	AA, BA, CA, DA, EA... (D, H, E, F, G...)	water	water		18.0	189	Chemie (HOH)

Sequence modifications

A, B, C, D, H, E, F, J, K, L: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Asp 40	Lys 41	engineered mutation
Lys 108	Gln 109	engineered mutation

G, I: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Lys 108	Gln 109	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	187041.1
Non-Polymers*	Number of molecules	11
	Total formula weight	3128.8
All*	Total formula weight	190169.9

*Water molecules are not included.