5U69
Polycomb protein EED in complex with inhibitor: (3R,4S)-1-[(2-methoxyphenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Polycomb protein EED | polymer | 369 | 42583.5 | 1 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (Human) | hEED,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 2 | A | (3R,4S)-1-[(2-methoxyphenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine | non-polymer | 363.5 | 1 | Chemie (LQD) | |||
| 3 | water | water | 18.0 | 511 | Chemie (HOH) |
Sequence modifications
A: 77 - 441 (UniProt: O75530)
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
| Ser 74 | - | expression tag |
| His 75 | - | expression tag |
| Met 76 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42583.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 363.5 | |
| All* | Total formula weight | 42947.0 |
