5U68

Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Chimera protein of Fusion glycoprotein F0 and Envelope glycoprotein	polymer	562	62452.5	3	UniProt (P03420) UniProt (M1E1E4) Pfam (PF00523) Pfam (PF07921)	Human respiratory syncytial virus A (strain A2)	Protein F
2	D, E, F (E, F, G)	MPE8	polymer	294	30684.7	3		Homo sapiens (Human)

Sequence modifications

A, B, C: 1 - 513 (UniProt: P03420)

PDB	External Database	Details
Ala 102	Pro 102	conflict
Cys 155	Ser 155	conflict
Phe 190	Ser 190	conflict
Leu 207	Val 207	conflict
Cys 290	Ser 290	conflict
Val 379	Ile 379	conflict
Val 447	Met 447	conflict
Ser 514	-	linker
Ala 515	-	linker
Ile 516	-	linker
Gly 517	-	linker

A, B, C: 518 - 545 (UniProt: M1E1E4)

PDB	External Database	Details
Gly 546	-	expression tag
Leu 547	-	expression tag
Val 548	-	expression tag
Pro 549	-	expression tag
Arg 550	-	expression tag
Gly 551	-	expression tag
Ser 552	-	expression tag
Ser 553	-	expression tag
Ala 554	-	expression tag
His 555	-	expression tag
His 556	-	expression tag
His 557	-	expression tag
His 558	-	expression tag
His 559	-	expression tag
His 560	-	expression tag
His 561	-	expression tag
His 562	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	279411.5
All*	Total formula weight	279411.5

*Water molecules are not included.