5U2E
BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bromodomain-containing protein 4 | polymer | 140 | 16412.9 | 2 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A, B | ethyl 4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzoate | non-polymer | 385.4 | 2 | Chemie (837) | |||
3 | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A, B: 42 - 180 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Gly 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 32825.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 770.9 | |
All* | Total formula weight | 33596.6 |