5U1T

Crystal structure of the Saccharomyces cerevisiae separase-securin complex at 2.6 angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Separin	polymer	1596	184044.5	1	UniProt (Q03018) Pfam (PF03568)	Saccharomyces cerevisiae (Baker's yeast)	Separase
2	B (B)	Securin	polymer	117	13366.6	1	UniProt (P40316) Pfam (PF04856)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
3	C (A)	water	water		18.0	16	Chemie (HOH)

Sequence modifications

A: 51 - 1630 (UniProt: Q03018)

PDB	External Database	Details
Met 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
Ser 42	-	expression tag
Gly 43	-	expression tag
Gly 44	-	expression tag
Ser 45	-	expression tag
Arg 46	-	expression tag
Ser 47	-	expression tag
Glu 48	-	expression tag
Ala 49	-	expression tag
His 50	-	expression tag

B: 258 - 373 (UniProt: P40316)

PDB	External Database	Details
Met 257	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	197411.1
All*	Total formula weight	197411.1

*Water molecules are not included.