5U1C
Structure of tetrameric HIV-1 Strand Transfer Complex Intasome
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, F, G (A, B, C, D) | HIV-1 Integrase, Sso7d chimera | polymer | 383 | 42320.3 | 4 | UniProt (A0A157T5S7) UniProt (F2WR39) Pfam (PF02022) Pfam (PF00665) Pfam (PF00552) UniProt (by SIFTS) (P12497) | Sulfolobus solfataricus | 7 kDa DNA-binding protein d, Sso7d |
2 | C, H (G, H) | DNA (11-MER) | polymer | 11 | 3349.2 | 2 | Homo sapiens | ||
3 | D, I (E, I) | DNA (23-MER) | polymer | 23 | 7015.5 | 2 | Human immunodeficiency virus 1 | ||
4 | E, J (F, J) | DNA (37-MER) | polymer | 37 | 11414.4 | 2 | Human immunodeficiency virus 1 | ||
5 | K, M (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | L, N (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B, C, D: -74 - -11 (UniProt: A0A157T5S7)
A, B, C, D: 1 - 288 (UniProt: F2WR39)
F, J: 1 - 21 (PDB: 5U1C)
F, J: 22 - 37 (PDB: 5U1C)
PDB | External Database | Details |
---|---|---|
Met -94 | - | expression tag |
Gly -93 | - | expression tag |
Ser -92 | - | expression tag |
Ser -91 | - | expression tag |
His -90 | - | expression tag |
His -89 | - | expression tag |
His -88 | - | expression tag |
His -87 | - | expression tag |
His -86 | - | expression tag |
His -85 | - | expression tag |
Ser -84 | - | expression tag |
Ser -83 | - | expression tag |
Gly -82 | - | expression tag |
Leu -81 | - | expression tag |
Val -80 | - | expression tag |
Pro -79 | - | expression tag |
Arg -78 | - | expression tag |
Gly -77 | - | expression tag |
Ser -76 | - | expression tag |
His -75 | - | expression tag |
Gly -10 | - | linker |
Gly -9 | - | linker |
Gly -8 | - | linker |
Gly -7 | - | linker |
Gly -6 | - | linker |
Gly -5 | - | linker |
Gly -4 | - | linker |
Gly -3 | - | linker |
Gly -2 | - | linker |
Gly -1 | - | linker |
Gly 0 | - | linker |
PDB | External Database | Details |
---|---|---|
Gln 152 | Glu 152 | engineered mutation |
F, J: 22 - 37 (PDB: 5U1C)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 212839.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 179.4 | |
All* | Total formula weight | 213018.7 |