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5U1C

Structure of tetrameric HIV-1 Strand Transfer Complex Intasome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, F, G
(A, B, C, D)
HIV-1 Integrase, Sso7d chimerapolymer38342320.34UniProt (A0A157T5S7)
UniProt (F2WR39)
Pfam (PF02022)
Pfam (PF00665)
Pfam (PF00552)
UniProt (by SIFTS) (P12497)
Sulfolobus solfataricus7 kDa DNA-binding protein d, Sso7d
2C, H
(G, H)
DNA (11-MER)polymer113349.22Homo sapiens
3D, I
(E, I)
DNA (23-MER)polymer237015.52Human immunodeficiency virus 1
4E, J
(F, J)
DNA (37-MER)polymer3711414.42Human immunodeficiency virus 1
5K, M
(A, C)
ZINC IONnon-polymer65.42Chemie (ZN)
6L, N
(A, C)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
A, B, C, D: -74 - -11 (UniProt: A0A157T5S7)
PDBExternal DatabaseDetails
Met -94-expression tag
Gly -93-expression tag
Ser -92-expression tag
Ser -91-expression tag
His -90-expression tag
His -89-expression tag
His -88-expression tag
His -87-expression tag
His -86-expression tag
His -85-expression tag
Ser -84-expression tag
Ser -83-expression tag
Gly -82-expression tag
Leu -81-expression tag
Val -80-expression tag
Pro -79-expression tag
Arg -78-expression tag
Gly -77-expression tag
Ser -76-expression tag
His -75-expression tag
Gly -10-linker
Gly -9-linker
Gly -8-linker
Gly -7-linker
Gly -6-linker
Gly -5-linker
Gly -4-linker
Gly -3-linker
Gly -2-linker
Gly -1-linker
Gly 0-linker
A, B, C, D: 1 - 288 (UniProt: F2WR39)
PDBExternal DatabaseDetails
Gln 152Glu 152engineered mutation
F, J: 1 - 21 (PDB: 5U1C)
F, J: 22 - 37 (PDB: 5U1C)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight212839.3
Non-Polymers*Number of molecules4
Total formula weight179.4
All*Total formula weight213018.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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