5TZN

Structure of the viral immunoevasin m12 (Smith) bound to the natural killer cell receptor NKR-P1B (B6)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, W	Killer cell lectin-like receptor subfamily B member 1B allele B	polymer	137	15631.5	2	UniProt (Q99JB4) Pfam (PF00059) In PDB	Mus musculus (Mouse)	CD161 antigen-like family member B,Inhibitory receptor NKR-P1B,Lymphocyte antigen 55d,Ly-55d,NKR-P1D,Natural killer cell surface protein NKR-P1B allele B6
2	F, G	Glycoprotein family protein m12	polymer	190	21217.2	2	UniProt (D3XDJ6) Pfam (PF12216) In PDB	Murid herpesvirus 1 (MuHV-1)
3	B, D, I	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	C	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
5	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
6	H	beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G57544ON)
7	F, G	IODIDE ION	non-polymer		126.9	2	Chemie (IOD)
8		water	water		18.0	34	Chemie (HOH)

Sequence modifications

A, W: 89 - 215 (UniProt: Q99JB4)

PDB	External Database	Details
Thr 87	-	expression tag
Gly 88	-	expression tag
Gly 118	Cys 118	engineered mutation
Gly 216	-	expression tag
Thr 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag

F, G: 29 - 208 (UniProt: D3XDJ6)

PDB	External Database	Details
Leu 27	-	expression tag
Glu 28	-	expression tag
Thr 209	-	expression tag
Ser 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73697.3
Branched	Number of molecules	6
	Total formula weight	2959.8
Non-Polymers*	Number of molecules	2
	Total formula weight	253.8
All*	Total formula weight	76910.8

*Water molecules are not included.