5TZN
Structure of the viral immunoevasin m12 (Smith) bound to the natural killer cell receptor NKR-P1B (B6)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, W) | Killer cell lectin-like receptor subfamily B member 1B allele B | polymer | 137 | 15631.5 | 2 | UniProt (Q99JB4) Pfam (PF00059) | Mus musculus (Mouse) | CD161 antigen-like family member B,Inhibitory receptor NKR-P1B,Lymphocyte antigen 55d,Ly-55d,NKR-P1D,Natural killer cell surface protein NKR-P1B allele B6 |
| 2 | B, C (F, G) | Glycoprotein family protein m12 | polymer | 190 | 21217.2 | 2 | UniProt (D3XDJ6) Pfam (PF12216) | Murid herpesvirus 1 (MuHV-1) | |
| 3 | E, G, J (B, D, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F (C) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 5 | H (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 6 | I (H) | beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G57544ON) | |||
| 7 | K, L (F, G) | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
| 8 | M, N, O, P (A, F, G, W) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, W: 89 - 215 (UniProt: Q99JB4)
F, G: 29 - 208 (UniProt: D3XDJ6)
| PDB | External Database | Details |
|---|---|---|
| Thr 87 | - | expression tag |
| Gly 88 | - | expression tag |
| Gly 118 | Cys 118 | engineered mutation |
| Gly 216 | - | expression tag |
| Thr 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Thr 209 | - | expression tag |
| Ser 210 | - | expression tag |
| His 211 | - | expression tag |
| His 212 | - | expression tag |
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73697.3 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2959.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 253.8 | |
| All* | Total formula weight | 76910.8 |
