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5TYR

X-ray crystal structure of wild type HIV-1 protease in complex with GRL-121

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Proteasepolymer9910803.82UniProt (C8B467)
Pfam (PF00077)
UniProt (by SIFTS) (G0X8E8)
Human immunodeficiency virus 1
2C
(A)
(3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamatenon-polymer670.81Chemie (7O7)
3D, E
(A, B)
waterwater18.0148Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21607.5
Non-Polymers*Number of molecules1
Total formula weight670.8
All*Total formula weight22278.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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